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Madecassoside, the active molecule of ancient Centella asiatica medicinal plant, is a proven skin-saver. Backed by science, it exhibits outstanding ability to repair irritated and sensitive skin and improve the appearance of aging skin.


Madecassoside is a natural ingredient derived from the Centella Asiaticaherb, commonly known as tiger grass or Indian pennywort. Centella Asiatica has been used for centuries in traditional Chinese medicine and its active molecule madecassoside recently gained popularity in the skincare industry for its ability to repair irritated and sensitive skin and to improve the appearance of aging skin.


The concentration of madecassoside in skincare products can vary, but it is typically used in concentrations of 0.5% to 2%.

Who Should Use It

Madecassoside is suitable for all skin types, but it is particularly beneficial for those with sensitive, irritated and weakened skin.

Can Be Used In Combination With

Madecassoside works well in combination with other active ingredients such as retinol, vitamin C, superoxide dismutase (SOD), vitamin B3, and azelaic acid. These ingredients enhance the benefits of madecassoside and create a synergistic effect for improved skin health.

How Often Can You Use It

Madecassoside can be used daily in the morning and/or evening

Don't Use It If

Madecassoside is suitable for all skin types. If you have very sensitive skin or allergies, it is always recommended to test products on a small skin area before using them on the face.

Origins of the Ingredient

Madecassoside is extracted from the Centella Asiatica plant, which is native to Asia and commonly found in swampy and marshy areas. This plant has been used for centuries in traditional medicine and is known for its healing and soothing properties. Universkin uses a synthetical madecassoside to have a consistent composition, quality, and high-purity active ingredient compared to plant extracts.

Chemical Composition

Madecassoside is a triterpenoid saponin, which is a type of natural compound that is responsible for the plant's therapeutic properties. It is a crystalline white powder.

Mechanism of Action

Madecassoside is one of the most studied terpenoids saponin in Centella asiatica with multiple biological activities in different types of cells. Madecassoside works by stimulating the production of collagen, which is the protein that gives skin its firmness and elasticity. It also helps to reduce oxidative stress and inflammation, which can cause skin damage and aging. Additionally, madecassoside helps to repair and strengthen the skin's barrier function, which protects it from environmental stressors and irritants.


The main benefits of madecassoside include improved skin health and appearance. It helps to repair irritated and sensitive skin, reducing the appearance of fine lines and wrinkles and improving skin firmness and elasticity. Additionally, madecassoside helps to soothe and calm irritated skin, reducing redness and oxidative stress. It also helps to improve the skin's barrier function, which can prevent further damage and promote a more youthful, radiant complexion.


Madecassoside is a stable ingredient.

In conclusion, Madecassoside is a versatile and effective ingredient that can help to repair and renew damaged and sensitive skin. It is suitable for all skin types, including sensitive and weakened skin, and can be used in combination with a range of other ingredients to enhance its effectiveness. When used as directed, Madecassoside can help to improve the appearance of fine lines and wrinkles, reduce redness and oxidative stress, and promote a brighter and more radiant complexion. If you are pregnant or breastfeeding, it is important to speak with your doctor before using Madecassoside to ensure its safe use for your specific needs.